There is a possibility of intergenerational inheritance in consanguineous marriage. Both parties in consanguineous marriage are likely to inherit the same disease causing genes from a common ancestor, which means that the likelihood of offspring developing the disease is higher than that of ordinary children. Genes can be either dominant or recessive. If a disease causing gene appears dominant in offspring, it will directly lead to disease in the offspring; If the pathogenic gene is recessive in the offspring, it only means that they may carry this gene, which may continue to be inherited in the offspring of the next generation.
Diseases that are prone to occur in offspring of consanguineous marriage
1. Congenital intellectual disability
2. Congenital heart disease
3. Congenital idiocy
4. Mediterranean anemia
5. Phenylketonuria
6. Hypertension
7. Albinism
8. Schizophrenia
9. Congenital heart disease
10. Epilepsy